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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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Cialis (tadalafil) can interact with some medications

  1. Nitrate-Related Erythromiannopoulos: tadalafil can increase blood pressure by blocking calcium channels in the penis, increasing the risk of fainting. Avoid combining tadalafil with nitrates or nitric oxide donors while taking this medication.
  2. Alpha-blockers: While Cialis can be taken with or without food, consuming it with or near the medication may increase side effects like dizziness or light-headedness.
  3. Other Drug-Food Interactions:Although there is a less severe interaction with these medications, eating a light meal before taking these substances can reduce their potential for altering effectiveness.
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Nitrates (e.g.

“Selling drugs that contain nitrates or nitric oxide donors in place of drugs that contain sildenafil citrate can be dangerous to your health,” says, a leading pharma company with over 40 years of experience in the pharmaceutical industry. “It’s a very risky business.”

Sildenafil citrate is one of the most popular drugs used to treat erectile dysfunction, a common problem for men worldwide. Nitric oxide is a chemical that relaxes the smooth muscle cells in the penis, increasing blood flow and the ability to achieve and maintain an erection. Nitric oxide is found in many prescription drugs and is the main component in Viagra and other drugs used to treat the problem. However, it is not the only component in nitrate medicines used for this purpose. Other examples of nitrates include,, and.

In recent years, several drugs have been found to cause erectile dysfunction, such as (Cialis), (Tadalafil), and (Levitra). The drugs are often prescribed to patients suffering from low libido and are used to treat pulmonary hypertension and heart failure.

“The most common reasons for this are physical,” says Dr. Michael Ricks, professor of clinical pharmacology and urology at Tufts College, and an expert in men’s health and medicine at Harvard-affiliated Brigham and Women’s Hospital. “In order for them to be effective, the drugs need to be in a healthy, well-balanced, and well-balanced solution.”

In addition to the nitrates, many of the drugs used in treating erectile dysfunction are also used to treat other conditions that affect the penis. The drugs are commonly prescribed to men with prostate cancer, high blood pressure, high cholesterol, or heart disease.

A study published in the Journal of Sexual Medicine in 2007 found that erectile dysfunction medications can cause sexual dysfunction in men who take nitrate drugs, including sildenafil (sold as Viagra) and nitroglycerin (Nigrelix).

“We found that men who take nitroglycerin for heart problems, high blood pressure, or diabetes, had a higher incidence of erectile dysfunction than men who do not take nitroglycerin,” says Dr. Peter L. Leopold, a urology specialist and clinical professor at Harvard Medical School. “This is a finding that may have important implications for the future of erectile dysfunction treatment in men.”

Dr. Leopold is a professor of urology at Harvard Medical School and an associate professor of urology at New York University. He is also an associate professor of medicine at the Boston University School of Medicine. He is a former chair of the department of urology at Boston’s Lenox Hill Hospital and director of the American Urological Association.

Leopold is a professor of urology at the Massachusetts General Hospital and a member of the urological faculty at Harvard Medical School and the urological team at Boston University Hospital.

Ricks said the results of the current study were the results of an independent study of nitroglycerin, a medication used to treat pulmonary hypertension. He said that the studies used the data from the previous study and others. He added that the current study included men who have diabetes.

“The nitroglycerin-induced erectile dysfunction study was designed to be used in a single-blind study,” he said. “It was designed to be used in the treatment of pulmonary hypertension.”

In the current study, patients who took sildenafil or sildenafil plus tadalafil were asked to participate in a four-week trial of one or two nitroglycerin tablets. Patients also received an identical amount of placebo for four weeks.

Researchers at Brigham and Women’s Hospital, Boston Medical Center, and Massachusetts General Hospital have conducted a series of randomized trials to investigate the safety and efficacy of sildenafil, the active ingredient in Viagra.

As with any drug product, there may be side effects. Generally, patients who experience side effects usually get them within 12 to 24 hours after taking Tadalafil. Side effects usually resolve on their own within 48 hours.

Most common Tadalafil side effects

  • Headache
  • Indigestion
  • Back pain
  • Muscle pain
  • Flushing
  • Stuffy nose

Some more serious side effects have been reported. While rare, it is important to stop taking Tadalafil and contact a doctor right away if any of the following occur:

  • An erection will not go away (priapism). If you have an erection that lasts longer than 4 hours, get medical help right away. If not treated right away, priapism can permanently damage the penis.
  • Sudden vision loss in one or both eyes. Sudden vision loss can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropath (NAION).
  • Sudden hearing decrease or hearing loss. Some may also have ringing in the eyes (tinnitus) or dizziness.

For a complete list of possible side effects,.

Possible drug interactions

Some drugs/medications may interact with Tadalafil. You should not take Tadalafil if you are taking nitrates (such as nitroglycerin tablets or patches) because the combination of these with Tadalafil could significantly lower blood pressure and lead to fainting or even death. Additionally, do not take Tadalafil if you are taking Cisapride, other ED medications (e.g. Viagra), Adcirca, or Riociguat.

On your intake form, please be sure to provide AgelessRx with all medications, herbs, non-prescription drugs, or dietary supplements you use. Also be sure to report if you smoke, drink alcohol, or use illegal drugs, as some may interact with your medication.

For a complete list of possible drug interactions,.

Other important safety information

Patients who have a condition called “left ventricular outlet obstruction” from valvular problems or heart muscle enlargement may get side effects such as fainting or light-headedness. Because patients with recent heart attacks or stroke, heart pains (angina), heart failure, uncontrolled blood pressure or uncontrolled irregular heart beats, severe liver disease, and retinal eye problems have not been studied, Tadalafil (Cialis) is not recommended for these patients. There may be rare occurrences of priapism or painful, prolonged erections. This is a serious condition that requires immediate medical attention. Patients should seek prompt medical attention if their erection lasts longer than four hours.

After taking a single tablet, Tadalafil can remain in the body for up to two days. It can remain longer if patients have problems with their kidneys or liver, or they are taking certain other medications.

Note:All information included on this page is a summary. It may not cover all possible information. If you have questions about this medication, talk to a doctor, pharmacist, or health care provider.

Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

  • Tadalafil is used to treat male erectile dysfunction (ED).
  • Patients with a history of blood clots or those at increased risk for this condition have had a stroke or a blood clot during treatment. Patients with a history of deep vein thrombosis (DVT) or a history of these conditions should be carefully followed-up with their doctors as soon as possible.
  • The risk of getting a stroke or developing a thrombotic event may increase with increasing duration of treatment. Patients should be advised to get anticoagulants regularly and to have regular blood tests.
  • Patients with a history of cancer or other serious liver conditions should be monitored closely during Tadalafil treatment. As soon as they have any suspicious liver function results, they should receive a prescription for Tadalafil from a doctor.

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Cialis Tablet 20s Uses

Treats erectile dysfunction in men. Works by increasing blood flow to the penis. It is used to treat pulmonary arterial hypertension (high blood pressure in the arteries of the lungs) and certain types of benign prostatic hyperplasia (a condition in which the prostate gland becomes enlarged). It is also used to prevent prostate enlargement in adult men with enlarged prostatic hypertrophy. This medication is known as Tadalafil. It belongs to a group of medicines called phosphodiesterase type 5 inhibitors. It works by relaxing the blood vessels in your penis, thereby increasing blood flow into your penis when you get sexually excited, ready for sex or for as long as you want. Cialis Tablet 20 mg Tablet also treats benign prostatic hyperplasia (BPH) by relaxing the bladder and prostate muscles. This medication also helps in treating male pattern baldness. It may take 1-4 months before you start to notice the effects of the full effects of this medication. It is important to continue using this product even after you have had your prostate tested by a doctor.

Lipitor is the name of a medication used to treat and some people develop erectile dysfunction.

The medication contains a drug called tadalafil, which works by improving blood flow to the penis. It is sold under the name Cialis or similar brand name medications, and is often used to treat erectile dysfunction.

It is available in the form of a film-coated tablet, which may be taken with or without food, but it is important to note that this drug is not an erectile dysfunction medication.

It is also available in the form of an oral liquid or tablet, and is usually taken on an empty stomach. It should be noted that it can take about 20 to 30 minutes for the medication to start working, but it is important to be aware of potential side effects and the timing of your next dose if you have taken it too soon.

In most cases, the effectiveness of the medication can be affected by several factors, including the underlying cause, and the individual’s medical history. It is crucial to consult with a healthcare professional before using any medication.

In addition to the risks associated with taking this medication, there are also potential side effects to be aware of. These can include headaches, facial flushing, and indigestion.

It is important to note that while the medication is safe for most people to use, it should only be used under the guidance of a healthcare professional. This may include a thorough evaluation by a healthcare professional to determine if it is appropriate for you.